Evolution of Cerebral Tumor Necrosis Factor-α Production During Human Ischemic Stroke

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Evolution of cerebral tumor necrosis factor-alpha production during human ischemic stroke.

BACKGROUND AND PURPOSE Tumor necrosis factor-alpha (TNF-alpha) is detected in ischemic brain cells in experimental animal models and is believed to play an important role in apoptosis. However, the natural expression of TNF-alpha during human stroke is not known. METHODS We examined TNF-alpha immunohistochemistry and terminal deoxynucleotidyl transferase-mediated dUTP nick-end labeling (TUNEL...

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Evolution of Cerebral Tumor Necrosis Factor-a Production During Human Ischemic Stroke

Background and Purpose—Tumor necrosis factor-a (TNF-a) is detected in ischemic brain cells in experimental animal models and is believed to play an important role in apoptosis. However, the natural expression of TNF-a during human stroke is not known. Methods—We examined TNF-a immunohistochemistry and terminal deoxynucleotidyl transferase–mediated dUTP nick-end labeling (TUNEL) in brain samples...

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ژورنال

عنوان ژورنال: Stroke

سال: 2001

ISSN: 0039-2499,1524-4628

DOI: 10.1161/01.str.32.8.1750